Neurovista

Comparative efficacy of different AAV viruses in the  primate striatum.  See article here.

Date:  Wednesday, November 5th, 2008
Time:  3:00pm-4:30 pm, Reception to Follow
Location:  Pechet Room
The Joseph B. Martin Conference Center
at Harvard Medical School
77 Avenue Louis Pasteur, Boston MA, 02115

“Current Issues in Human Gene Therapy”
David Williams, M.D.
 Director of Translational Research, Children’s Hospital
Chief, Division of Hematology/Oncology, Children’s Hospital Boston,
Leland Fikes Professor of Pediatrics, Harvard Medical School
 
“Using Gene Therapy as a Platform for Pediatricians
to Manufacture Drugs for Pediatric Cancer”
Laurence  J.N. Cooper,  M.D., Ph.D.
Grant Taylor,  W. W. Sutow and Margaret Sullivan Distinguished Professor in  Pediatrics
M.D. Anderson  Cancer  Center
Section Chief, Cell  Therapy, Children’s  Cancer Hospital
Director,  Immunology  Laboratory of  Physician Scientists

“Integrating and Non-integrating Retrovirus Based Vectors for Cell Modification”
Christopher Baum, M.D.
Professor,  Experimental   Haematology
Head, Department of  Experimental  Haematology
Hannover  Medical  School
Adjunct Professor of  Pediatrics
Cincinnati  Children’s  Hospital Research  Foundation

See ne-ns.com for more information

Research Recruit University of Florida

April 15th, 2008 · No Comments

Researcher joins UF Brain Institute
Gainesville Sun – Apr 11, 2008
MBI Director Dennis Steindler describes the addition of Brent Reynolds as a professor of neurosurgery “a real coup.” Reynolds joined the UF faculty from the University of Queensland, Australia, on March 1. He will run the newly created Adult Stem Cell …

cvsection.org is a new website providing links and information for the Joint CV Section

Hypothermia draws renewed interest after football player’s injury.

Neural Stem Cell Study Reveals Mechanism That May Play Role In Cancer

Science Daily — In the dynamic world of the developing brain, neural stem cells give rise to neurons deep within the brain’s fluid-filled ventricles. These newborn neurons then migrate along the stem cell fibers up to the neocortex, the seat of higher cognitive functions. Now, scientists have discovered a key mechanism of this migration — one that may also play an important role in other developmental processes and diseases, including cancer……

Neuronal subtype specification in the cerebral cortex.

Molyneaux BJ, Arlotta P, Menezes JR, Macklis JD.

MGH-HMS Center for Nervous System Repair, Department of Neurosurgery, Program in Neuroscience, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

In recent years, tremendous progress has been made in understanding the mechanisms underlying the specification of projection neurons within the mammalian neocortex. New experimental approaches have made it possible to identify progenitors and study the lineage relationships of different neocortical projection neurons. An expanding set of genes with layer and neuronal subtype specificity have been identified within the neocortex, and their function during projection neuron development is starting to be elucidated. Here, we assess recent data regarding the nature of neocortical progenitors, review the roles of individual genes in projection neuron specification and discuss the implications for progenitor plasticity.

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An excellent review on the topic.

• Long term monitoring of human neural stem cells by MRI
• Creating CNS progenitors from ES cells
• From the Adult to Rat Brain:  Transplantation of Stem Cells
• Correlation of Nestin Expression with Glioma Outcome

PREDICTORS OF NEUROSURGICAL CAREER CHOICE AMONG RESIDENTS AND RESIDENCY APPLICANTS..
Authors: Lawton, Michael T. M.D.; Narvid, Jared M.D.; Quinones-Hinojosa, Alfredo M.D.
[Neurosurgery – Current Table Of Contents]

OLFACTORY GROOVE MENINGIOMAS: CLINICAL OUTCOME AND RECURRENCE RATES AFTER TUMOR REMOVAL THROUGH THE FRONTOLATERAL AND BIFRONTAL APPROACH..
Authors: Nakamura, Makoto M.D.; Struck, Melena Cand. Med.; Roser, Florian M.D.; Vorkapic, Peter M.D., Ph.D.; Samii, Madjid M.D., Ph.D.
[Neurosurgery – Current Table Of Contents]

THE ROLE OF RACE IN TIME TO TREATMENT AFTER SUBARACHNOID HEMORRHAGE..
Authors: Eden, Sonia V. M.D.; Morgenstern, Lewis B. M.D.; Sekar, Padmini M.S.; Moomaw, Charles J. Ph.D.; Haverbusch, Mary R.N., B.S.N., C.N.R.N.; Flaherty, Matthew L. M.D.; Broderick, Joseph P. M.D.; Woo, Daniel M.D., M.S.
[Neurosurgery – Current Table Of Contents]

MOLECULAR GENETICS OF MENINGIOMAS: FROM BASIC RESEARCH TO POTENTIAL CLINICAL APPLICATIONS..
Authors: Simon, Matthias M.D.; Bostrom, Jan P. M.D.; Hartmann, Christian M.D.
[Neurosurgery – Current Table Of Contents]

Trophism of neural progenitor cells to embryonic stem cells: Neural induction and transplantation in a mouse ischemic stroke model.. Embryonic stem cell (ESC)-derived products have emerged as a promising cell source for neuroregeneration. C17.2 neural precursor cells were noted to express genes of neurotrophins and neuroprotective factors and to be enable to enhance proliferation, neuritogenesis, and differentiation of SH-SY5Y and SK-N-AS neuroblasts, suggesting their neurotrophic potential. We used C17.2 cells as neurotrophic chaperones to induce ESCs, D3, and E14TG2a into neural lineage cells. Significantly greater numbers of Sox-2(+), Musashi-1(+), and nestin(+) neurospheres developed in noncontact cocultures than in cultures of ESCs without C17.2 support or with 50% conditioned medium after 8 days. Immunoreactivit [PubMed: neural stem cell]

Neurosurgeons May Be Eligible for Federal Funds for Emergency Care Costs [AANS Current News]

‘Humanity it what binds us’: Neurosurgeon combines skill, compassion – Shreveport Times. “If I weren’t doing this, I’d be a history and literature professor,” said Nanda, professor of surgery and chairman of the department of Neurosurgery at LSU . [neurosurgery neurosurgeon – Google News]